Synthesis and aqueous organization of 1,
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J.R. Deverre; A. Gulik; Y. Letourneux; P. Couvreur; J.P. Benoit
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Article
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1991
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Elsevier Science
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English
β 802 KB
1,3-dipalmitoyl-2-(4-aminobutyryl)glycerol β’ HCI, a diglyceride ester of 7-aminobutyric acid (GABA), was synthesized with a good yield (46.5%). This prodrug ( 1,3-dp-GABA " HCI) was highly amphiphilic and formed stable dispersions in water. The thermodynamic parameters of the endothermic transition