The C-3 brominated and iodinated derivatives were prepared from the corresponding 2-arylquinolin-4(1H)-ones and their NMe-4-oxo derivatives using pyridinium tribromide in acetic acid or iodine-Na 2 CO 3 mixture in THF. The results of further studies of chemical transformation of the prepared Ξ±-haloe
Synthesis and Further Studies of Chemical Transformation of the 2-Aryl-3-halogenoquinolin-4(1H)-one Derivatives.
β Scribed by Malose J. Mphahlele; Mutshinyalo S. Nwamadi; Peace Mabeta
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 24 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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New derivatives of 3,4-dihydrospiro[cycloalkane- \(1^{\prime}, 2(1 H)\)-quinolines] were obtained from cycloheptanone and cyclooctanone via facile three steps hetero spiro annulation process. Their nitro derivatives were prepared through electrophilic substitution reactions.
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