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4-Methyl-3,4-dihydrospiro[cycloheptane-1′,2(1H)-quinoline] and 4-methyl-3,4-dihydrospiro[cyclooctane-1′,2(1H)-quinoline]. synthesis of derivatives and chemical transformations

✍ Scribed by Alirio Palma; Wilson Rozo; Elena Stashenko; Daniel Molina; Vladimir Kouznetsov

Publisher: Journal of Heterocyclic Chemistry
Year: 1998
Tongue: English
Weight: 448 KB
Volume: 35
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570350135

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✦ Synopsis

New derivatives of 3,4-dihydrospiro[cycloalkane- (1^{\prime}, 2(1 H))-quinolines] were obtained from cycloheptanone and cyclooctanone via facile three steps hetero spiro annulation process. Their nitro derivatives were prepared through electrophilic substitution reactions.

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