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Synthesis and free radical scavenging activity of 4-(2H-1,2,4-benzothiadiazine-1,1-dioxide-3-yl)-2,6-bis(1,1-dimethylethyl)phenols

✍ Scribed by Annalisa Tait; Stefano Ganzerli; Maria Di Bella

Publisher: Elsevier Science
Year: 1996
Tongue: French
Weight: 429 KB
Volume: 52
Category: Article
ISSN: 0040-4020
DOI: 10.1016/0040-4020(96)00747-8

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## Abstract A new method for the preparation of 4‐substituted 3,4‐dihydro‐1__H__‐2,1,3‐benzothiadiazine 2,2‐dioxides is described. Treatment of __t__‐butyl __N__‐phenylsulfamoylcarbamate derivatives (**1**) with different aldehydes afforded the corresponding intramolecular cyclized products **2** u