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Synthesis and first in vitro cytotoxicity studies of bis(2-chloroethyl) amino group containing polymers. Pharmacologically active polymers: 22

✍ Scribed by Peter Molz; Helmut Ringsdorf; George Abel; Peter J. Cox

Book ID
119069681
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
478 KB
Volume
2
Category
Article
ISSN
0141-8130

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✍ Laurent Fontaine; Céline Marbœuf; Jean-Claude Brosse; Martine Maingault; Frédéri 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 447 KB

## Abstract Hydrosoluble poly(3,6,9‐trioxaundecamethylene phosphonate) with attached cytotoxic bis(2‐chloroethyl)amine in the side chain was synthesized by chemical modification of the corresponding polyphosphonate via the Atherton‐Todd reaction. The structure of the product was confirmed by ^1^H,