Synthesis and evaluation of the pharmacological activity of rigid analogs of sympathomimetic catecholamines derived from bicyclo[2.2.1]heptane
โ Scribed by Balsamo, A.; Breschi, M. C.; Lapucci, A.; Macchia, B.; Macchia, F.; Martinotti, E.; Nencetti, S.; Nieri, P.; Orlandini, E.
- Book ID
- 126880286
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 583 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-2623
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๐ SIMILAR VOLUMES
Three prostaglandin endoperoxide analogs that possess the 2,3-diazabicyclo[2.2.1]heptane skeleton were synthesized and evaluated for activity in human platelets and in the rat fundus. All three compounds were inactive in inhibiting or stimulating platelet aggregation. One compound possessed weak con
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