Synthesis and biological evaluation of f
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Jeffrey J. Ares; Pamela E. Outt; Jared L. Randall; Jeffrey N. Johnston; Peter D.
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Article
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1996
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Elsevier Science
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English
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Several analogs of the gastroprotective molecule flavone have been synthesized and evaluated for gastroprotective activity. A C2-C3 double bond and an intact C ring appear necessary for optimum activity. Activity can be retained by replacing the 2-phenyl substituent with other groups but is eliminat