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Synthesis and evaluation of novel polysaccharide-Gd-DTPA compounds as contrast agent for MRI

✍ Scribed by Guoying Sun; Jianghua Feng; Fengying Jing; Fengkui Pei; Maili Liu


Book ID
114226299
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
222 KB
Volume
265
Category
Article
ISSN
0304-8853

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Synthesis of Gd-DTPA-cholesterol: a new
✍ Luciano Lattuada; Giovanna Lux πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 196 KB

A straightforward and efficient synthesis of Gd-DTPA-cholesterol is reported. This new lipophilic gadolinium complex can be easily incorporated into mixed micelles in order to achieve MRI contrast agents with increased relaxivity. These supramolecular systems can find potential application in magnet