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Synthesis and evaluation of novel macrocyclic antifungal peptides

✍ Scribed by Monique P.C. Mulder; John A.W. Kruijtzer; Eefjan J. Breukink; Johan Kemmink; Roland J. Pieters; Rob M.J. Liskamp


Book ID
113495438
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
961 KB
Volume
19
Category
Article
ISSN
0968-0896

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Synthesis and antifungal evaluation of n
✍ Braulio Insuasty; Alberto Insuasty; Alexis Tigreros; Jairo Quiroga; Rodrigo Abon πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 122 KB

## Abstract This work describes the synthesis and antifungal evaluation of 5‐arylidene‐(__Z__)‐2‐(1,1‐dicyanomethylene)‐1,3‐thiazol‐4‐ones 5 obtained from the reaction of 2‐(1,1‐dicyanomethylene)‐1,3‐thiazol‐4‐one 3 and benzaldehydes 4. The starting material 3 was synthesized by a condensation reac