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Synthesis and evaluation of nitro 5-deazaflavins as novel bioreductive antitumor agents

✍ Scribed by Tetsuji Kawamoto; Yoshihiro Ikeuchi; Junko Hiraki; Yoshiteru Eikyu; Kazue Shimizu; Masaki Tomishima; Kiyoshi Bessho; Fumio Yoneda; Yuji Mikata; Mamiko Nishida; Kenji Ikehara; Takuma Sasaki


Book ID
108038885
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
318 KB
Volume
5
Category
Article
ISSN
0960-894X

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Synthesis and Biological Evaluation of N
✍ Chuanfei Jin; Yong-Ju Liang; Hongwu He; Liwu Fu πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 110 KB πŸ‘ 2 views

## Abstract A series of novel (thio)ureas containing the pyrimidinyl group was designed and synthesized. Their __in‐vitro__ antitumor activity against different human tumor cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further studies o