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Synthesis and Biological Evaluation of Novel (Thio)Urea Derivatives as Potential Antitumor Agents

✍ Scribed by Chuanfei Jin; Yong-Ju Liang; Hongwu He; Liwu Fu


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
110 KB
Volume
344
Category
Article
ISSN
0365-6233

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✦ Synopsis


Abstract

A series of novel (thio)ureas containing the pyrimidinyl group was designed and synthesized. Their in‐vitro antitumor activity against different human tumor cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further studies on structure modification.


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