Synthesis and Biological Evaluation of Novel (Thio)Urea Derivatives as Potential Antitumor Agents
β Scribed by Chuanfei Jin; Yong-Ju Liang; Hongwu He; Liwu Fu
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 110 KB
- Volume
- 344
- Category
- Article
- ISSN
- 0365-6233
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β¦ Synopsis
Abstract
A series of novel (thio)ureas containing the pyrimidinyl group was designed and synthesized. Their inβvitro antitumor activity against different human tumor cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further studies on structure modification.
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