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Synthesis and Evaluation of Macrocyclic Gadolinium Chelates as Hepatospecific MRI Agents

✍ Scribed by Marinelli, Edmund R.; Neubeck, Richard; Song, Bo; Wagler, Thomas; Ranganathan, Ramachandran S.; Sukumaran, Kozikhott; Wedeking, P.; Nunn, A.; Runge, V.; Tweedle, M.


Book ID
123317934
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
387 KB
Volume
9
Category
Article
ISSN
1076-6332

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Gd( DTPA)\*-(diethylenetriaminepentaacetic acid) and the polyaza macrocyclic Gd(D0TA)-(1,4,7,10-tetraazacyclododecane-N,N',N",N) are paradigms of general purpose paramagnetic complexes useful for enhancing contrast in magnetic resonance imaging (MRI). It is of both fundamental and practical interest