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Synthesis and Evaluation of Esters of N, N-Bis(2-chloroethyl)-p-aminophenol and N,N-Bis(2-bromoethyl)-p-aminophenol as Potential Antitumor Agents

โœ Scribed by Vickers, S.; Hebborn, P.; Moran, J.; Triggle, D.


Book ID
126934254
Publisher
American Chemical Society
Year
1969
Tongue
English
Weight
412 KB
Volume
12
Category
Article
ISSN
0022-2623

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In order to search for novel antitumor drugs with high activity and low toxicity, a series of new compounds, galactopyranosyl (or glucofuranosyl) N,N-bis(Z-chloroethyl) phosphoramidates, have been synthesized. The structures of all compounds prepared were proved by ' H NMR, 31P NMR, IR, and M S spec