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On the formation of estrone lactam esters of N,N-bis(2-chloroethyl)aminocinnamic acid isomers, p-N,N-bis(2-chloroethyl)aminophenylbutyric acid and their antitumor activity

โœ Scribed by P. Catsoulacos; G. Pairas; A. Papageorgiou


Book ID
112131292
Publisher
Journal of Heterocyclic Chemistry
Year
1995
Tongue
English
Weight
224 KB
Volume
32
Category
Article
ISSN
0022-152X

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โœ Ru-Yu Chen; Xiao-Ru Chen ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 459 KB

In order to search for novel antitumor drugs with high activity and low toxicity, a series of new compounds, galactopyranosyl (or glucofuranosyl) N,N-bis(Z-chloroethyl) phosphoramidates, have been synthesized. The structures of all compounds prepared were proved by ' H NMR, 31P NMR, IR, and M S spec