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Synthesis and evaluation of cardiotonic activity of simple butenolides II

✍ Scribed by M Medarde; E Caballero; F Tomé; A García; MJ Montero; R Carrón; A San Feliciano


Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
516 KB
Volume
28
Category
Article
ISSN
0223-5234

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ChemInform Abstract: Synthesis and Cardi
✍ V. SEDEREVICIUTE; V. GARALIENE; P. VAINILAVICIUS; A. HETZHEIM 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB

Synthesis and Cardiotonic Activity of Pyrazolylpyrimidines. -The title compounds are screened for cardiotonic activity. Many of them exhibit positive effects. The most positive-inotropic effects show compounds (VIII). The ED 50 values are comparable to those of milrinone. -(SEDEREVICIUTE, V.;