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Synthesis and Evaluation of Acyl-Chain- and Galactose-6′′-Modified Analogues of α-GalCer for NKT Cell Activation

✍ Scribed by Ming-Han Hsieh; Dr. Jung-Tung Hung; Ya-Wen Liw; Yin-Jen Lu; Prof. Dr. Chi-Huey Wong; Prof. Dr. Alice L. Yu; Prof. Dr. Pi-Hui Liang


Book ID
112016127
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
437 KB
Volume
13
Category
Article
ISSN
1439-4227

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Activation of invariant NKT cells by αGa
✍ Roberto Furlan; Alessandra Bergami; Daniela Cantarella; Elena Brambilla; Masaro 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB

## Abstract Invariant NKT (inv. NKT) cells co‐express an invariant α β T cell receptor and the NK receptor NK1.1 and, upon CD1d‐restricted recognition of the glycosphingolipid antigen α‐galactosyl ceramide (αGalCer), secrete large amounts of regulatory cytokines. We investigated whether αGalCer‐dep