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Synthesis and Evaluation of a Set of 4-Phenylpiperidines and 4-Phenylpiperazines as D 2 Receptor Ligands and the Discovery of the Dopaminergic Stabilizer 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine (Huntexil, Pridopidine, ACR16)

✍ Scribed by Pettersson, Fredrik; Pontén, Henrik; Waters, Nicholas; Waters, Susanna; Sonesson, Clas


Book ID
118001363
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
988 KB
Volume
53
Category
Article
ISSN
0022-2623

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✍ Marcia I. Dawson; Peter D. Hobbs; Albert Dorsky; Hiromi Morimoto 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 484 KB

## Abstract The synthesis of [1′,3′‐^3^H]4‐(4′‐azido‐5′,6′,7′,8′‐tetrahydro‐5′,5′,8′,8′‐tetramethyl ‐2′‐anthracenyl)benzoic acid is described. This retinoid was designed as a photoaffinity probe of the receptor sites of cellular retinoic acid‐binding protein and the nuclear retinoic acid receptor p