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Synthesis and effects of some novel tetrahydronaphthalene derivatives on proliferation and nitric oxide production in lipopolysaccharide activated Raw 264.7 macrophages

✍ Scribed by A. Selen Gurkan; Arzu Z. Karabay; Zeliha Buyukbingol; Erdem Buyukbingol


Book ID
108116537
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
948 KB
Volume
46
Category
Article
ISSN
0223-5234

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A new pyrrolidinone diterpenoid, excisusin F (1), was isolated from the aerial parts of Isodon excisus (Lamiaceae), together with four known compounds, and their structures were determined mainly by NMR (1D and 2D) and mass spectrometry. Excisusin F (1) and inflexarabdonin E (3) showed potent inhibi