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Synthesis and effects of conjugated tocopherol analogues on peptide nucleic acid hybridisation

✍ Scribed by Browne, Elisse C.; Langford, Steven J.; Abbott, Belinda M.

Book ID
121195625
Publisher
Royal Society of Chemistry
Year
2013
Tongue
English
Weight
339 KB
Volume
11
Category
Article
ISSN
1477-0520

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## Abstract Peptide nucleic acids (PNAs) are DNA mimics with a neutral peptide backbone instead of the negatively charged sugar phosphates. PNAs exhibit several attractive features such as high chemical and thermal stability, resistance to enzymatic degradation, and stable binding to their RNA or D