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Synthesis and dopamine D2-like receptor binding affinity of substituted 5-phenyl-pyrrole-3-carboxamides

✍ Scribed by Gérard A Pinna; Maria M Curzu; Mario Sechi; Giorgio Chelucci; Elisabetta Maciocco


Book ID
114019516
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
168 KB
Volume
54
Category
Article
ISSN
0014-827X

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2-[(substituted)phenyl]-5-[1-(2-phenylaz
✍ David Bolton; Izzy Boyfield; Martyn C. Coldwell; Michael S. Hadley; Amanda Johns 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 192 KB

A series of 2-1(substituted)phenyl]-5-[1-(2-phenylazacycloheptyl)methyl]-lH-pyrroles (8 -15) has been prepared to investigate the effect on affinity and selectivity for the dopamine D 3 receptor of modifying the substituent in the phenyl ring at the 2-position of the pyrrole. Sulfonate 7 and sulfona