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Synthesis and cytotoxic activity of novel imidazo[1,2-a]pyridines and quinolines

✍ Scribed by M.A. Vilchis-Reyes; M.A. Martinez-Urbina; E. Diaz Torres; A. Guzmán Sánchez

Book ID
119598936
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
89 KB
Volume
6
Category
Article
ISSN
1359-6349

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Solid-phase synthesis of imidazo[1,2-a]p
Solid-phase synthesis of imidazo[1,2-a]pyridines and imidazo[1,2-a]pyrimidines
✍ Saı̈d El Kazzouli; Sabine Berteina-Raboin; Abderrahim Mouaddib; Gérald Guillaume 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 409 KB

The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.