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Synthesis and Cytotoxic Activity of 6-(Substituted-Phenyl)Amino-5,8-Quinazolinediones

โœ Scribed by Chung-Kyu Ryu; You-Jin Yi; Ik Hwa Choi; Mi Jin Chae; Ja-Young Han; Ok-Jai Jung; Chong-Ock Lee


Publisher
Springer-Verlag
Year
2004
Tongue
English
Weight
343 KB
Volume
13
Category
Article
ISSN
1054-2523

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Synthesis and Cytotoxic Activities of 6-Chloro-7-arylamino-5,8isoquinolinediones. -A convenient method for the synthesis of the title isoquinolinediones (VI) (12 examples) starting from commercially available 5-nitroisoquinoline (I) is given. These new isoquinoline derivatives, especially the oxyph