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Synthesis and crystal structure of maleopimaric acid

โœ Scribed by Rao, Xiaoping; Song, Zhanqian; Yao, Xujie; Han, Chunrui; Shang, Shibin


Book ID
120289586
Publisher
Taylor and Francis Group
Year
2008
Tongue
English
Weight
337 KB
Volume
22
Category
Article
ISSN
1478-6419

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## Abstract A new hepatoprotective agent, Nโ€(2โ€hydroxyethyl)โ€maleopimarimidyl morpholide (RU18492) has been synthesised labelled with tritium at Cโ€3, Cโ€4a, Cโ€10 and in the Cโ€isopropyl group. The incorporation of tritium relies on the acidโ€catalysed isomerisation of levopimaric acid (4) to abietic a