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Synthesis and Crystal Structure of a New Schiff Base 4-[(2-hydroxy-benzylidene)-amino]-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide

✍ Scribed by Annamalai Subashini; Madhukar Hemamalini; P. Thomas Muthiah; Gabriele Bocelli; Andrea Cantoni


Publisher
Springer
Year
2008
Tongue
English
Weight
366 KB
Volume
39
Category
Article
ISSN
1572-8854

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We have previously shown that (RS)-2-amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-yl)isoxazol-4-yl]propionic acid (2-Me-Tet-AMPA) is a selective agonist at (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) receptors, markedly more potent than AMPA itself, whereas the isomeric com