Synthesis and crystal structure of 1-phenyl-3-methylthio-4-imino-5-allyl-pyrazolo[3,4-d]pyrimidine
โ Scribed by Weiqiang Chen; Linhong Weng; Guiyu Jin
- Book ID
- 110275436
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 56 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1572-8854
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## Abstract Pyrazoloโ[3,4โ__d__]pyrimidineโ4,6โdiones **5** and pyrazolo[4,3โ__d__]pyrimidineโ5,7โdiones **7** were synthesized by Curtius rearrangement of pyrazolic monoโesters **2** and **3** followed by heteroโcyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.
The title compound, C 14 H 12 N 4 O 3 , a pyrazolopyrimidine derivative, displays normal geometrical parameters. The dihedral angle between the mean planes of the pyrazolopyrimidine unit and the phenyl ring is 26.14 (4) . The non-H atoms of the ester side chain are coplanar (r.m.s. deviation = 0.009
Geometric parameters of the title compound, C 14 H 12 N 4 O 3 , a pyrazolopyrimidine derivative, are in the usual ranges. The dihedral angle between the pyrazolopyrimidine system and the phenyl ring is 4.64 (5) . The non-H atoms of the ester side chain lie in a common plane (r.m.s. deviation = 0.028