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Synthesis and complete assignment of NMR data of 20 chalcones

✍ Scribed by Doseok Hwang; Jiye Hyun; Geunhyeong Jo; Dongsoo Koh; Yoongho Lim


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
96 KB
Volume
49
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

Chalcones, intermediates in flavonoid biosynthesis, can exhibit antibacterial, antiproliferative, and anti‐inflammatory properties. Chalcones contain two benzene rings and both hydroxylated and methoxylated analogs are frequently produced by hydroxylases and O‐methyltransferases in plant biosynthetic pathways. Assignments of NMR peaks in the spectra of hydroxylated and/or methoxylated chalcones can help in identifying novel chalcone derivatives isolated from natural sources by referencing these data against NMR spectra obtained from known chalcones. We report here the syntheses of 20 chalcones and complete assignments of ^1^H and ^13^C NMR spectra. Copyright © 2010 John Wiley & Sons, Ltd.


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