## Abstract Six flavone derivatives were studied. Previously reported NMR data of three of these derivatives were corrected and the NMR data for the other three derivatives not studied previously were completely assigned on the basis of the basic 1D and 2D NMR experiments and molecular modeling. Co
Complete assignments of NMR data of 13 hydroxymethoxyflavones
✍ Scribed by Younghee Park; Byoung-Ho Moon; Heejung Yang; Youngshim Lee; Eungjung Lee; Yoongho Lim
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 104 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.2063
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✦ Synopsis
Abstract
Diosmetin, 5,7,3′‐trihydroxy‐4′‐methoxyflavone shows chemopreventive, antimutagenic, and antiallergic effects. On the other hand, chrysoeriol, 5,7,4′‐trihydroxy‐3′‐methoxyflavone induced nodABC‐lacZ in Rhizobium meliloti. Both of them belong to hydroxymethoxy‐ flavones. One major difference between diosmetin and chrysoeriol is the substituted position of hydroxyl and methoxyl groups. In order to elucidate the relationships between their structures and activity, one of the first things to be done is the determination of their structures. However, most flavones occur widely in nature, and thus it is difficult to obtain in sufficient amounts from natural sources to identify their structures. Assignments of NMR data of several hydroxymethoxyflavones may help us to identify novel flavonoid compounds isolated from natural sources based on their NMR experiments. Therefore, we report here the complete assignments of ^1^H and ^13^C NMR data of 13 hydroxymethoxyflavones. Copyright © 2007 John Wiley & Sons, Ltd.
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