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Complete assignments of NMR data of 13 hydroxymethoxyflavones

✍ Scribed by Younghee Park; Byoung-Ho Moon; Heejung Yang; Youngshim Lee; Eungjung Lee; Yoongho Lim


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
104 KB
Volume
45
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

Diosmetin, 5,7,3′‐trihydroxy‐4′‐methoxyflavone shows chemopreventive, antimutagenic, and antiallergic effects. On the other hand, chrysoeriol, 5,7,4′‐trihydroxy‐3′‐methoxyflavone induced nodABC‐lacZ in Rhizobium meliloti. Both of them belong to hydroxymethoxy‐ flavones. One major difference between diosmetin and chrysoeriol is the substituted position of hydroxyl and methoxyl groups. In order to elucidate the relationships between their structures and activity, one of the first things to be done is the determination of their structures. However, most flavones occur widely in nature, and thus it is difficult to obtain in sufficient amounts from natural sources to identify their structures. Assignments of NMR data of several hydroxymethoxyflavones may help us to identify novel flavonoid compounds isolated from natural sources based on their NMR experiments. Therefore, we report here the complete assignments of ^1^H and ^13^C NMR data of 13 hydroxymethoxyflavones. Copyright © 2007 John Wiley & Sons, Ltd.


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