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Synthesis and chemical reactivity of some 1,2,4-Thiadiazolo[2,3-a]-pyrimidines and related compounds

✍ Scribed by B. Korea; B. Stanovnik; M. Tišler


Book ID
112124089
Publisher
Journal of Heterocyclic Chemistry
Year
1977
Tongue
English
Weight
338 KB
Volume
14
Category
Article
ISSN
0022-152X

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## Abstract 2‐Alkyl‐, 2‐aryl‐, and 2‐halo‐substituted derivatives of 7‐methyl‐6‐fluoro‐1,3,4‐thiadiazolo[3,2‐__a__]pyrimidin‐6‐one (**3**) were prepared by reaction of 2‐substituted 5‐amino‐1,3,4‐thiadiazoles (**1**) and ethyl 2‐fluoroacetoacetate (**2**) in polyphosphoric acid. A convenient proced