The synthesis and characterization of di-nbutyl-, tri-n-butyl-and triphenyltin gibberellates are reported. Their antitumour activities in vitro against a panel of seven human tumour cell lines are given and compared with those of drugs used clinically.
Synthesis and characterization of novel organotin monomers and copolymers and their antibacterial activity
โ Scribed by Nayef S. Al-Muaikel; Salem S. Al-Diab; Ali A. Al-Salamah; Ali M. A. Zaid
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 133 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0021-8995
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โฆ Synopsis
Two novel organotin monomers, (N-tri-n-butyltin) maleimide and m-acryloylamino-(tri-n-butyltin benzoate), were synthesized. Copolymerization of these two monomers with styrene was carried out in the bulk at 65ยฐC using asobisisobutyronitrile as the free radical initiator. The monomers and copolymers were characterized by elemental analysis; the molecular weights of the copolymers were determined by GPC, solubility, IR, and 1 H-NMR spectral studies. The antibacterial activities of the synthesized organotin monomers and copolymers toward various types of bacteria were also reported.
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