✦ LIBER ✦

Synthesis and characterization of isotopically labelled drugs

✍ Scribed by Frans M. Kaspersen; Jan F. Vader; Carel W. Funke; Eric M. G. Sperling

Book ID: 104589501
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 593 KB
Volume: 112
Category: Article
ISSN: 0165-0513
DOI: 10.1002/recl.19931120218

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✦ Synopsis

Abstract

The article describes approaches for the synthesis and analysis of isotopically (^2^H, ^3^H, ^13^C, ^14^C, ^35^S) labelled drugs necessary for the development of a pharmacologically active compound into a registered drug.

Special features such as isotope effects, radiolysis and ^3^H NMR spectra are discussed.

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