Synthesis and Characterization of DOTA-(amide)4 Derivatives: Equilibrium and Kinetic Behavior of Their Lanthanide(III) Complexes
✍ Scribed by Azhar Pasha; Gyula Tircsó; Enikő Tircsóné Benyó; Ernő Brücher; A. Dean Sherry
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 229 KB
- Volume
- 2007
- Category
- Article
- ISSN
- 1434-1948
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Project supported by the National N d Science Foundation d China (No. #xmrm).
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## Abstract Eu^3+^, Dy^3+^, and Yb^3+^ complexes of the dota‐derived tetramide __N__,__N′__,__N″__,__N′′′__‐[1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetrayltetrakis(1‐oxoethane‐2,1‐diyl)]tetrakis[glycine] (H~4~dotagl) are potential CEST contrast agents in MRI. In the [Ln(dotagl)] complexes, the Ln^