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Synthesis and Characterization of Bradykinin B 2 Receptor Agonists Containing Constrained Dipeptide Mimics

✍ Scribed by Amblard, Muriel; Daffix, Isabelle; Bergé, Gilbert; Calmès, Monique; Dodey, Pierre; Pruneau, Didier; Paquet, Jean-Luc; Luccarini, Jean-Michel; Bélichard, Pierre; Martinez, Jean

Book ID
127015378
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
507 KB
Volume
42
Category
Article
ISSN
0022-2623

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Lys analogues of bradykinin, have been determined by highresolution NMR in a zwitterionic lipoid environment. Radical-induced relaxation of the 1 H NMR signals was used to probe the topological orientation of the peptides with respect to the zwitterionic lipid interface. The radical-induced relaxati