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Synthesis and characterization of azolate gold(i) phosphane complexes as thioredoxin reductase inhibiting antitumor agents

✍ Scribed by Galassi, Rossana; Burini, Alfredo; Ricci, Simone; Pellei, Maura; Rigobello, Maria Pia; Citta, Anna; Dolmella, Alessandro; Gandin, Valentina; Marzano, Cristina


Book ID
120201408
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
302 KB
Volume
41
Category
Article
ISSN
1477-9226

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The reactions of water-soluble phosphanes P(CH,OH), (1) and Ph2PCH20H (2) with NaAuC14 in aqueous or alcoholic media, produced the water/alcoholic-soluble Au' complexes [Au(P(CH,OH),),]+ (3) and [Au(Ph2PCH20H):J+ (4) in near quantitative yields. The X-ray structures of 3 and 4, reported in this pape