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Synthesis and Characterization of 8-Methoxy-2'-Deoxyadenosine-Containing Oligonucleotides to Probe the Syn Glycosidic Conformation of 2'-deoxyadenosine Within DNA

โœ Scribed by Eason, R. G.; Burkhardt, D. M.; Phillips, S. J.; Smith, D. P.; David, S. S.


Book ID
126183146
Publisher
Oxford University Press
Year
1996
Tongue
English
Weight
92 KB
Volume
24
Category
Article
ISSN
0305-1048

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The near-UV-induced photoreaction of the bifunctional 8-methoxypsoralen (8-MOP) with 2'-deoxyadenosine (dAdo) was investigated in the dry state. Four main monoadducts of 8-MOP to 2'-deoxyadenosine were separated by high performance liquid chromatography and subsequently characterized by soft ionizat