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Synthesis and Characterization of 5-Substituted Novel Isoxazolidines Derived from 1,3-Dipolar Cycloaddition of Nitrones with Olefins: Studies of Antibacterial and Antifungal Activities

✍ Scribed by Ravi Kumar, K. R.; Mallesha, H.; Rangappa, K. S.


Book ID
120510902
Publisher
Taylor and Francis Group
Year
2003
Tongue
English
Weight
223 KB
Volume
33
Category
Article
ISSN
0039-7911

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✍ Hong-Kui Zhang; Wing-Hong Chan; Albert W. M. Leeb; Wai-Yeung Wong πŸ“‚ Article πŸ“… 2008 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 445 KB πŸ‘ 1 views

## Abstract magnified image Asymmetric 1,3‐dipolar cycloadditions of chiral nitrones to 1‐propene‐1,3‐sultone (**1**) were investigated. Chiral nitrones **6a‐e** reacted with sultone **1** in toluene at 90 Β°C for 24‐36 h to give the corresponding isoxazolidines in moderate yields with high regiose