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1,3-Dipolar cycloaddition reactions of nitrones with vinylacetic olefins in the racemic series and synthesis of δ-lactams via isoxazolidines

✍ Scribed by Josette Chanet-Ray; Marie Odile Charmier-Januario; Roger Vessière; Marie Zuccarelli

Book ID: 112131100
Publisher: Journal of Heterocyclic Chemistry
Year: 1994
Tongue: English
Weight: 398 KB
Volume: 31
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570310666

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## Abstract magnified image Asymmetric 1,3‐dipolar cycloadditions of chiral nitrones to 1‐propene‐1,3‐sultone (**1**) were investigated. Chiral nitrones **6a‐e** reacted with sultone **1** in toluene at 90 °C for 24‐36 h to give the corresponding isoxazolidines in moderate yields with high regiose