Synthesis and characterization of 1,4-dihydropyridine- substituted metallophthalocyanines
✍ Scribed by Karimi, Ali Reza; Bagherian, Fatemeh; Sourinia, Meysam
- Book ID
- 120631613
- Publisher
- Royal Society of Chemistry
- Year
- 2013
- Tongue
- English
- Weight
- 365 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0959-9436
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## Abstract The preparation of a novel series of quinoxaline‐substituted 1,4‐dihydropyridines is described. Thus, the reaction of 1 with acetoacetates in the presence of ammonia leads to dialkyl 2,6‐dimethyl‐4‐(quinoxaline‐1,4‐dioxid‐2‐yl)‐1,4‐dihydropyridine‐3,5‐dicarboxylates 2a‐g. Compounds 4a‐c
has been achieved via a novel asymmetric Michael addition of an optically pure vinylogous amide to an a,b-unsaturated ketone. The overall process is three steps from readily available starting materials and provides an economical manufacturing route to the title compound, which was required as a can