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Synthesis and Biophysical Studies of Modified Oligonucleotides Containing Acyclic Amino Alcohol Nucleoside Analogs

โœ Scribed by Ramasamy, Kanda S.; Stoisavljevic, Vesna

Book ID
126579486
Publisher
Taylor and Francis Group
Year
1999
Tongue
English
Weight
784 KB
Volume
18
Category
Article
ISSN
0732-8311

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Novel oligonucleotide dimers containing hydroxamate linkages (15 and 16) were synthesized, incorporated into oligonucleotide sequences and studied for their hybridization properties with complementary DNA and RNA targets. The modiยฎed oligonucleotides showed similar binding properties and enhanced re