Synthesis and Biological Properties of Novel Triazolopyrimido-pyrimidine-5,8-diones
โ Scribed by Anna Dlugosz
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 279 KB
- Volume
- 322
- Category
- Article
- ISSN
- 0365-6233
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๐ SIMILAR VOLUMES
To a cold (-78'C) solution of 10 mmoles of the iithium derivative ( I ) , RI=CH3, in tetrahydrofuran 111 was added with stirring 1.06 g (10 mmoles) of benzonitrile. The resulting bright orange mixture was kept at -78 O C for 40 min, after which the bath was removed and stirring was continued for an
## 2-Acetylbenzothiazole (1) reacts with dimethylformamide dimethylacetal (DMF-DMA) to afford the enaminone 2. Compound 2 reacts regioselectively with some nitrilimines 5a-d and nitrile oxides 6b-d to afford the novel pyrazole and isoxazole derivatives 11a-d and 12b-d, respectively, which react wi