Pentaethylbenzoic acid was produced in good yield bv saponification of the amide with 100% phosphoric acid, while under the same conditions pentamethylbenzamide was completely decarboxylated to pentamethylbenzene. The cyclisation of o-(pentaethylbenzoy1)-benzoic acid yielded an alkaline soluble, ye
✦ LIBER ✦
Synthesis and Biological Properties of L-Arginyl-L-Prolyl-L-Prolyl-Glycyl-L-Phenylalanyl-L-Seryl-L-Phenylalanyl-L-Arginine, an Octapeptide related to Bradykinin
✍ Scribed by NICOLAIDES, E. D.; DEWALD, H. A.; SHORLEY, PATRICIA G.; COLLIER, H. O. J.
- Book ID
- 109610780
- Publisher
- Nature Publishing Group
- Year
- 1960
- Tongue
- English
- Weight
- 223 KB
- Volume
- 187
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/187773a0
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Synthèse de la L-arginyl-L-prolyl-L-prol
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Synthèse de la L-arginyl-L-prolyl-L-prol
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R. A. Boissonnas; St. Guttmann; P.-A. Jaquenoud
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## Abstract The synthesis of a nonapeptide exhibiting bradykinin‐like properties is described. Condensation of CBO‐(nitro)Arg‐Pro‐OH with H‐Pro‐Gly‐NHNH‐CTO and selective splitting of the CTO‐group yielded CBO‐(nitro)Arg‐Pro‐Pro‐Gly‐NHNH~2~. CBO‐Phe‐ Ser‐N~2~ was condensed with H‐Pro‐Phe‐(nitro)Arg