Synthesis and biological properties of 2-(4-chlorophenyl)-3-morpholin-4-yl-(4-alkoxyphenyl)alkanol hydrochlorides
โ Scribed by O. A. Papoyan; N. K. Gasparyan; R. G. Paronikyan; A. A. Tatevosyan; D. A. Avakimyan; G. A. Panosyan; G. A. Gevorgyan
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 104 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0091-150X
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๐ SIMILAR VOLUMES
The synthesis of the title compound is described. It involves base catalyzed substitution of deuterium for hydrogen in 3-p- -chlorophenylglutaric acid which is subsequently transformed to baclofen. The overall yield is 80%. ## INTRODUCTION AND DISCUSSION In order to develop a mass fragmentographi
## Abstract A series of novel 3โ(coumarinโ4โyl)tetrahydroisoxazoles **5a,b, 7, 9** and 3โ(coumarinโ4โyl)dihydropyraโzoles **13aโd, 14,15a,b** were synthesized from coumarinโ4โcarboxaldehyde **1** __via__ the intermediate __N__โmethyl nitrone **3** and __N__โphenyl or __N__โmethyl hydrazones **11a,b