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Synthesis and biological investigations of some 5H-1,3,4-oxadiazolo[3,2-a]pyrimidin-5-ones

✍ Scribed by Farid S. G. Soliman; Ragab M. Shafik; Magda Darwish


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
551 KB
Volume
71
Category
Article
ISSN
0022-3549

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Synthesis of 2-Oxo-2H-[1,2,4]oxadiazolo-
✍ Urs Hengartner; Jean-Claude Muller; Henri Ramuz πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 German βš– 242 KB πŸ‘ 1 views

## Abstract Thermal cyclization of the pyrimidine‐__N__‐oxide dicarbamate **2** gives a 95:5 mixture of the 2‐oxo‐2__H__‐[1,2,4]oxadiazolo[2,3‐__a__]‐ and [2,3‐__c__]pyrimidinecarbamates **3** and **4.** An efficient procedure for the conversion of **3** to **4**, and __vice versa__, is described.