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Synthesis and biological evaluation of the L-enantiomer of 2′-deoxy-5-ethyl-4′-thiouridine

✍ Scribed by David L. Selwood; Keith Carter; Robert J. Young; Karamjit S. Jandu


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
180 KB
Volume
6
Category
Article
ISSN
0960-894X

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Synthesis and Biological Evaluation of 2
✍ Pieter E. Joos; Eddy L. Esmans; Roger A. Dommisse; André De Bruyn; Jan M. Balzar 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 German ⚖ 549 KB

## Abstract A new protected 2‐deoxy‐D‐ribose derivative, 5‐__O__‐[(__tert__‐butyl)diphenylsilyl]‐2‐deoxy‐3,4‐__O__‐ isopropylidene‐__aldehydo__‐D‐ribose (5), was synthesized starting from 2‐deoxy‐D‐ribose. This compound was coupled with 2‐lithio‐4‐(4,5‐dihydro‐4,4‐dimethyloxazol‐2‐yl)pyridine givin