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Synthesis and biological evaluation of tc-99m-cyclopentadienyltricarbonyltechnetium-labeled octreotide

✍ Scribed by Todd W. Spradau; W.Barry Edwards; Carolyn J. Anderson; Michael J. Welch; John A. Katzenellenbogen

Book ID
117688312
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
318 KB
Volume
26
Category
Article
ISSN
0969-8051

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The synthesis of Tc-99m-labeled, modified RNA is reported. This new class of radiopharmaceuticals is of potential interest as target specific imaging agents. The preparation of NaS-conjugated RNA was achieved by coupling S-protected MAG2-units to amino modified RNA in solution or on solid support. T