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Synthesis and biological evaluation of novel99mTc-oxo and99mTc-nitrido complexes with phenylalanine dithiocarbamate for tumor imaging

✍ Scribed by Zhu, Jingjing; Wang, Yue; Li, Zhenxiang; Fang, Si’an; Zhang, Junbo

Book ID
125364986
Publisher
Springer
Year
2014
Tongue
English
Weight
307 KB
Volume
302
Category
Article
ISSN
1588-2780

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## Abstract The novel dithiocarbamate derivative of metronidazole, potassium 2‐(2‐methyl‐5‐nitro‐1__H__‐imidazolyl)‐ethyl‐dithiocarbamate (MNIE‐DTC), was synthesized as the pharmacophore‐containing bifunctional ligand. The corresponding asymmetrical ^99m^Tc‐nitrido complex, expected as a tumor hypo