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Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors

✍ Scribed by Rossella Fioravanti; Adriana Bolasco; Fedele Manna; Francesca Rossi; Francisco Orallo; Francesco Ortuso; Stefano Alcaro; Roberto Cirilli

Book ID
108116523
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
377 KB
Volume
45
Category
Article
ISSN
0223-5234

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✍ M. Abdur Rahim; P. N. Praveen Rao; Edward E. Knaus πŸ“‚ Article πŸ“… 2002 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 62 KB

## Abstract A group of 1,2‐diphenyl‐3,5‐dioxopyrazolidines possessing a methylsulfonyl (**11**) or sulfonamide (**15**) substituent at the __para__ position of the __N__^1^‐phenyl ring, in conjunction with a hydrogen, methyl or fluoro sub‐stituent at the __para__ position of the __N__^2^‐phenyl rin