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Synthesis and biological evaluation of N-antipyrine-4-substituted amino-3-chloromaleimide derivatives

✍ Scribed by Fernanda Mahle; Tatiana da Rosa Guimarães; Aleandra Vergilina Meira; Rogério Corrêa; Rosana Cé Bella Cruz; Alexandre Bella Cruz; Ricardo José Nunes; Valdir Cechinel-Filho; Fátima de Campos-Buzzi


Book ID
108116480
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
512 KB
Volume
45
Category
Article
ISSN
0223-5234

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Preparation and biological evaluation of
✍ Albert J. Forlano; Robert L. S. Amai 📂 Article 📅 1966 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB

A series of N-amino acid substituted derivatives of serotonin was prepared. The method entailed condensing the or-halo analogs of alanine, isoleucine, phenylalanine, and valine with 5-benzyloxy-serotonin using a method adapted from Fisher's peptide synthesis. The activity of these compounds was comp