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Synthesis and Biological Evaluation of Integrin Antagonists Containing trans- and cis-2,5-Disubstituted THF Rings

✍ Scribed by Frank Osterkamp; Burkhard Ziemer; Ulrich Koert; Matthias Wiesner; Peter Raddatz; Simon L. Goodman

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 383 KB
Volume: 6
Category: Article
ISSN: 0947-6539
DOI: 10.1002/(sici)1521-3765(20000218)6:4<666::aid-chem666>3.0.co;2-z

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## Abstract magnified image A series of 2‐(4‐hydroxyphenyl)‐4,5‐disubstituted imidazoles (**1a**, **1b**, **1c**, **1d**, **1e**) prepared from α‐diketones, ammonium acetate, and __p__‐hydroxybenzaldehyde, which were glucosylated by using α‐acetobromoglucose to form 2‐(4‐__O‐__β‐D‐2,3,4,6‐tetra‐__