✦ LIBER ✦

Synthesis and biological evaluation of dinucleoside methylphosphonates of 3′-azido-3′-deoxythymidine and 2′, 3′-dideoxycytidine

✍ Scribed by Frédéric Puech; Gilles Gosselin; Jan Balzarini; Steven S. Good; Janet L. Rideout; Erik De Clercq; Jean-Louis Imbach

Book ID: 118001256
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 679 KB
Volume: 14
Category: Article
ISSN: 0166-3542
DOI: 10.1016/0166-3542(90)90062-c

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

13C NMR spectra of antiviral nucleosides

13C NMR spectra of antiviral nucleosides' 3′-azido-3′-deoxythymidine, 2′,3′-dideoxyadenosine, 2′,3′-dideoxycytidine and 2′,3′-dideoxyinosine

✍ G. W. Buchanan; K. Bourque 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 179 KB

NMR chemical shifts and one-bond ' 3C-1 H couplings are reported for B'azido-3'-deoxythymidine, 2',3'-dideoxyadenosine, 2',3'-dideoxycytidine and 2 ' 3dideoxyinosine. Unambiguous assignments were made on the basis of results from 2D INADEQUATE experiments to establish the carbon-carbon connectivitie

Synthesis of tritium-labelled 3′-azido-3

Synthesis of tritium-labelled 3′-azido-3′-deoxythymidine

✍ G.V. Sidorov; Yu.B. Zverkov; N.F. Myasoedov; M.V. Jasko; Yu.S. Skoblov 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 97 KB

## Abstract New approaches to the synthesis of 3′‐azido‐3′‐deoxythymidine labelled with tritium in the heterocyclic base have been developed. With this aim, enzymatic transribosylation with [^3^H]thymine using the enzyme preparation from rat liver and a three‐step chemical synthesis with use of the

3″-Azido-3′-Deoxythymidine and 2′,3′-Did

3″-Azido-3′-Deoxythymidine and 2′,3′-Dideoxycytidine Do Not Inhibit Gene-Specific DNA Repair in Hamster Cells

✍ C.J. Link; V.A. Bohr 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 361 KB

Potent and Selective Anti-HIV Activity o

Potent and Selective Anti-HIV Activity of 5-Chloro-Substituted Derivatives of 3′-Azido-2′,3′-Dideoxycytidine, 3′-Fluoro-2′,3′-Dideoxycytidine, and 2′,3′-Didehydro-2′,3′-Dideoxycytidine

✍ JAN BALZARINI; ARTHUR VAN AERSCHOT; PIET HERDEWIJN; ERIK DE CLERCQ 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB

New Dinucleoside Phosphonate Derivatives

New Dinucleoside Phosphonate Derivatives as Prodrugs of 3′-Azido-3′-Deoxythymidine and β -L-2′,3′-Dideoxy-3′-Thiacytidine: Synthesis and Anti-HIV Properties

✍ Solyev, Pavel N.; Jasko, Maxim V.; Karpenko, Inna L.; Sharkin, Yury A.; Shipitsy 📂 Article 📅 2014 🏛 Taylor and Francis Group 🌐 English ⚖ 480 KB

Syntheses and Biological Activities of P

Syntheses and Biological Activities of Polymers Containing 3′-Azido-3′-deoxythymidine

✍ Choi, Won-Moon; Lee, Neung-Ju; Ha, Chang-Sik; Cho, Won-Jei 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 361 KB 👁 2 views

The new monomer, 5@-O-methacryloyl-3@-azido-3@-deoxythymidine (MAZT), was synthesized by the reaction of methacryloyl chloride and 3@-azido-3@-deoxythymidine (AZT). Poly(MAZT) and copolymers of MAZT with vinyl acetate (VAc) and maleic anhydride (MAH) were synthesized by radical polymerizations. The