## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Biological Evaluation of 4-Methylideneisoxazolidin-5-ones — A New Class of Highly Cytotoxic α-Methylidene-γ-Lactones.
✍ Scribed by Marek Rozalski; Urszula Krajewska; Mariusz Panczyk; Marek Mirowski; Barbara Rozalska; Tomasz Wasek; Tomasz Janecki
- Book ID
- 102008543
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 21 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A novel series of 4‐substituted 1‐{[4‐(10,15,20‐triphenylporphyrin‐5‐yl)phenyl]methylidene}thiosemicarbazide, **4a**–**4n**, was synthesized in 9–21% yield by the condensation of 4‐(10,15,20‐triphenylporphyrin‐5‐yl)benzaldehyde (**3**) with various substituted thiosemicarbazides in pres